Life is good...
The PCI Latency Patch was my solution
(http://download.viahardware.com/vlatency_v019.zip)
I also installed the latest via-4-1 (4.38).
Now I can run PTLE in parallell with pulsar running 3MV, sample player and poison with 4 voices.
I also tried to see how many MV I could load. I ran ...